Diagnostic accuracy of point-of-care testing methods for SARS-CoV-2 detection in community quarantine and isolation settings.

ABSTRACT: Reverse transcriptase polymerase chain reaction (RT-PCR) testing has been regarded as the gold standard for the diagnosis of coronavirus disease 2019 (COVID-19). In response to the sudden surge in cases that overwhelmed the healthcare system in Hong Kong, several point-of-care testing (POCT) methods have been developed for rapid COVID-19 screening. However, the diagnostic accuracy of these methods remains inadequately established. COVID-19-positive patients and negative control subjects were recruited from a community isolation centre and individuals under home quarantine. Four nasal swab samples were collected by trained operators from each subject. Three swab samples were immediately tested using conventional COVID-19 rapid antigen test (RAT), fluorescence-based RAT (Fluorescent-RAT) and

SUBMITTER: Lam SC 

PROVIDER: S-EPMC12731264 | biostudies-literature | 2026 Mar

REPOSITORIES: biostudies-literature