The NICE experience of designing and utilising severity weights.

ABSTRACT:

Background

In January 2022, NICE changed from "End of Life" (EoL) to "severity" weights, whereby additional value is applied within cost effectiveness analysis to health benefits arising from health technologies deemed to qualify This study examines the relationship between these concepts, how they relate to patient age, and whether the new system is cost-neutral as intended.

Methods

Data was extracted from 555 NICE Technology Appraisal decisions from 2009 to 2024. Absolute (AS) and proportional shortfall (PS) severity indicators were estimated for pre 2022 decisions. Post 2022 decisions were judged against EoL criteria.We describe the relationship between severity weights, including the constituent AS and PS elements, age and EoL. Comparisons are made between the distributi

SUBMITTER: Wailoo A 

PROVIDER: S-EPMC12731295 | biostudies-literature | 2026 Jun

REPOSITORIES: biostudies-literature