The Effect of Adjunctive Antimicrobial Photodynamic Therapy in the Treatment of Peri-Implant Diseases: Systematic Review and Meta-Analysis.

ABSTRACT: Background/Objectives: Peri-implant diseases may occur around osseointegrated implants and lead to implant loss. Treatment strategies focus on infection control with decontamination of implant surfaces/pockets. Mechanical debridement (MD) is necessary to reduce biofilm, although it may have limited effects. Antimicrobial photodynamic therapy (aPDT) has been proposed to increase the potential of MD. The aim of this systematic review and meta-analysis is to evaluate aPDT in adjunct to MD versus MD as a single treatment. Methods: An electronic and hand literature search was performed in several databases up to March 2025 to include randomized controlled trials (RCTs). Risk of bias (RoB) was assessed by Cochrane Risk of Bias Tool for RCTs (RoB 2). A meta-analysis was performed wi

SUBMITTER: Nastri L 

PROVIDER: S-EPMC12731462 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature