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Long-Term Follow-Up and Risk of PCOS in Indiana Girls with a History of Premature Adrenarche-A Single Center Experience.


ABSTRACT: Background/Objectives: The aim of this study was to investigate rates of self-reported Polycystic Ovary Syndrome (PCOS), metabolic abnormalities and age of menarche in girls with a history of Premature Adrenarche (PA) and the association of baseline characteristics with these outcomes. Methods: A retrospective chart review of girls with PA seen between 2005 and 2015 was conducted. Eligible patients (or their mothers in girls <18 years of age) were surveyed by telephone to query whether they had developed PCOS, diabetes, pre-diabetes, hypertension or dyslipidemia as well as their age of menarche. Associations of baseline characteristics with PCOS or metabolic abnormalities were analyzed. Results: A total of 359 patients with PA were identified, of whom 118 completed a t

SUBMITTER: Saroufim R 

PROVIDER: S-EPMC12731558 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature