Canadian Prostate Cancer Trends in the Context of PSA Screening Guideline Changes.

ABSTRACT: Prostate cancer is the most diagnosed cancer among Canadian men, except non-melanoma skin cancers. Prostate-specific antigen (PSA) screening can enable early detection, but it is not formally recommended in Canada. Nonetheless, opportunistic screening persists, influenced by US practices and some Canadian guidelines that support screening. This study provides a detailed analysis of trends in prostate cancer incidence, mortality, stage distribution, and net survival in the context of evolving PSA screening guidelines. Prostate cancer case (1984-2022) and death (1984-2023) data were primarily from the Canadian Cancer Registry and the Canadian Vital Statistics Death database, respectively. Joinpoint regression identified incidence and mortality trends. Net survival was determined using the Po

SUBMITTER: Wilkinson AN 

PROVIDER: S-EPMC12731625 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature