A Systematic Review of Cutaneous Hypopigmentation Disorder Associated with Neurologic Involvement.

ABSTRACT: Background/Objectives: Cutaneous hypopigmentation is a common clinical sign observed in a variety of disorders. It may be congenital or acquired, localized or diffuse, and can range from benign to being associated with systemic conditions, including those affecting the central nervous system. Recognition of the key clinical features associated with each disorder is essential for accurate diagnosis and for differentiating one condition from another. Methods: PubMed, Embase, and Scopus databases were used to prepare a systematic review. Search terms were: "congenital", "cutaneous", "localized", "diffuse", "hypopigmentation" and "neurological disorders/signs". The focus was on congenital cutaneous hypopigmentation, distinguishing between localized and diffuse presentations, with

SUBMITTER: Pavone P 

PROVIDER: S-EPMC12731714 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature