Patient and Public Involvement in Paediatric Pragmatic Randomized Controlled Trials: A Mixed Methods Study.

ABSTRACT:

Background/objectives

Patient and public involvement (PPI) in the design, conduct, and dissemination of pragmatic trials may make trial results more relevant and meaningful. The nature of PPI in paediatric pragmatic trials has been poorly characterized in the literature. This study examined the prevalence and nature of PPI in paediatric pragmatic trials and lessons learned from researchers' experiences.

Methods

For this mixed methods study, we conducted an online survey and semi-structured interviews with corresponding authors of published paediatric pragmatic trials, identified using an online search filter in MEDLINE. Descriptive statistics and qualitative thematic analysis were used to analyse the data.

Results

PPI was reported by 71/127 (56%) survey respondents. R

SUBMITTER: Vanderhout S 

PROVIDER: S-EPMC12731746 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature