Multidetector Computed Tomography and Aortic Stenosis: The Emerging Potential of Bridging Morphology and Severity Grading.

ABSTRACT: Background/Objectives: Echocardiography is the reference standard for grading aortic stenosis (AS); however, it yields discordant severity estimates in up to 40% of patients. Multidetector computed tomography (MDCT)-derived methods for calculating aortic valve area (AVA) may improve diagnostic concordance, but their diagnostic performance, validation against invasive hemodynamics, and the influence of left ventricular outflow tract (LVOT) morphology on severity grading remain insufficiently investigated. Methods: We retrospectively analyzed 307 patients with normal-flow, high-gradient calcific AS who underwent echocardiography, MDCT, and cardiac catheterization. AVA was calculated using (1) echocardiographic LVOT diameter, (2) hybrid Doppler-MDCT planimetric LVOT area, and (3

SUBMITTER: Cordoni G 

PROVIDER: S-EPMC12731794 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature