Urine Cytological Diagnostics: Possibilities and Limitations-A 25-Year Review and Overview at Hannover Medical School.

ABSTRACT:

Background

Urine cytology is a highly effective, straightforward, and cost-efficient diagnostic tool for identifying neoplastic and non-neoplastic changes in the bladder, ureter, and renal pelvis. The aim of this study is to demonstrate the high sensitivity and specificity of urine cytology in detecting a wide range of urothelial lesions, including metastatic involvement.

Material and methods

Urine cytology was performed on 9639 cases between 2000 and 2025. The samples, collected from patients, were processed at the Institute of Pathology. Cytological slides were prepared using cytocentrifugation and stained with May-Grünwald-Giemsa (MGG) and Papanicolaou stains. The cytological findings were classified according to WHO, 2004 compared with histological specimens. Additionall

SUBMITTER: Bisharah S 

PROVIDER: S-EPMC12732187 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature