Social well-being moderates behavioral therapy response for generalized anxiety disorder.

ABSTRACT:

Introduction

Identifying moderators of treatment outcome for depression and anxiety offers promise for personalizing treatment or providing novel intervention targets. Indices of social well-being have emerged as candidate moderators due to their robust impact on mental health and quality of life. Here, we examine whether measures of social support, isolation, and loneliness moderate outcomes to behavioral activation (BA) and exposure-based therapy (EXP) for individuals with GAD.

Methods

This secondary analysis of a randomized clinical trial included 69 participants (31 EXP, 38 BA). Participants completed the GAD-7, along with NIH PROMIS (Depression; Social Isolation; and Emotional, Instrumental, and Informational Support) and NIH Toolbox (Friendship; Loneliness) scales. Reg

SUBMITTER: Armstrong JD 

PROVIDER: S-EPMC12732314 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature