Design of a Prospective Human-Animal Cohort Study to Evaluate the Role of Camels and Other Livestock Species in the Transmission of <i>Brucella</i> spp. to Humans in Kenya.

ABSTRACT: Brucellosis remains a major zoonotic disease worldwide, with disproportionate burden in low- and middle-income countries where limited veterinary and healthcare infrastructure constrain effective control measures. However, its pathways of transmission are poorly understood. In pastoralist settings, we hypothesize that camels have a high burden of Brucella spp. and play a key role in spreading it to humans and other livestock. This manuscript presents a study protocol to quantify the relative contribution of various livestock species to brucellosis transmission and identify cost-effective control strategies in Kenya. Using probability-proportional-to-size sampling, we aimed to recruit a longitudinal cohort of 170 households and their herds per site in the Marsabit and Kajiado countie

SUBMITTER: Oketch D 

PROVIDER: S-EPMC12733042 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature