Distribution Analysis of the Lifespan Trait in Drosophila.

ABSTRACT: Research into longevity and aging involves comparing the size of cohorts at certain points on survival curves. However, this analysis is oversimplified because it provides limited information about the sample structure and the distribution of lifespan as a trait. Here, we introduce a method for estimating lifespan across the entire data range using distribution analysis. More specifically, we propose dividing the lifespan series into intervals, obtaining the frequencies of phenotypes by lifespan within the sample, followed by distribution analysis using the normality criterion. Additionally, to visualize the differences, we propose describing the resulting distributions formally using the normal distribution function and the β-distribution function. We demonstrate that the proposed methodo

SUBMITTER: Yumuhova CA 

PROVIDER: S-EPMC12733365 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature