The Association Between Vitamin D Levels and Erectile Dysfunction in Men: A Systematic Review.

ABSTRACT: Background/Objectives: Erectile dysfunction (ED) is a common sexual disorder in men, frequently linked to endothelial dysfunction affecting penile vasculature. Accumulating evidence suggests that vitamin D (VD) status may influence endothelial function and, consequently, erectile function. VD deficiency has also been associated with cardiovascular risk factors, which are well-known contributors to ED. Methods: A systematic review following PRISMA guidelines was conducted, analyzing studies from PubMed and Cochrane databases published between 2010 and 2025. Randomized controlled trials, observational studies, and pilot clinical trials examining the relationship between VD levels and ED in the general male population were included. Results: Out of 1335 identified article

SUBMITTER: Matukaitiene R 

PROVIDER: S-EPMC12733428 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature