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Rethinking Potassium Management in Chronic Kidney Disease-A Modern Approach.


ABSTRACT: Potassium homeostasis is impaired in patients with chronic kidney disease (CKD) due to alterations in physiological mechanisms and use of agents that modulate the renin angiotensin aldosterone system (RAAS) to slow CKD progression and reduce cardiovascular risk. In recent years, a new paradox has emerged: while dietary potassium restriction has been dogmatically recommended to prevent hyperkalemia, emerging evidence suggests that a more liberated potassium intake may offer potential benefits, particularly in patients with early CKD. This has prompted a paradigm shift towards a more individualized approach to the management of hyperkalemia in CKD. This review aims to provide an overview of the latest management strategies for hyperkalemia in CKD and to summarize the current literature inclu

SUBMITTER: Kog ZX 

PROVIDER: S-EPMC12733500 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature