Outcomes of Liver Transplantation in Incidental Intrahepatic Cholangiocarcinoma and Combined Hepatocellular-Cholangiocarcinoma: An Exceptional Perspective from a Single-Center Experience.

ABSTRACT: Background/Objectives: Intrahepatic cholangiocarcinoma (ICC) and combined hepatocellular-cholangiocarcinoma (CHC) have historically been considered a contraindication for liver transplantation (LT) due to poor prognosis. However, incidental ICC/CHC has been reported in small amounts of patients undergoing LT. Methods: A retrospective cohort study was conducted to analyze patients undergoing LT with incidental ICC/CHC at our center between January 2010 and December 2021. Results: 28 patients including 12 incidental ICCs and 16 CHCs on explant were identified. Median follow-up after LT was 63 months and 13 patients died due to tumor recurrence. The 1-, 3-, and 5-year survival rates for the whole group were 85.7%, 64.3%, and 53.3%, respectively. There was no significant d

SUBMITTER: Ma L 

PROVIDER: S-EPMC12733566 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature