Pleiotropic Function of Antenna-Specific Odorant-Binding Protein Links Xenobiotic Adaptation and Olfaction in <i>Leptinotarsa decemlineata</i>.

ABSTRACT: The Colorado potato beetle (CPB) is the primary defoliator of potatoes and is notorious for its ability to develop resistance to various insecticides. This remarkable adaptability may partly reflect selective pressures imposed due to the beetle's coevolution with toxic Solanaceous host plants. As the initial interface between the environment and the insect olfactory system, odorant-binding proteins (OBPs) may sequester excess harmful molecules, such as insecticides and plant allelochemicals, in the perireceptor space, mitigating deleterious effects on vulnerable olfactory sensory neuronal dendrites. In this study, we identified an antenna-specific OBP (LdecOBP33) that is significantly upregulated in a pesticide resistant strain compared to a susceptible one. Competitive displacement

SUBMITTER: Abendroth JA 

PROVIDER: S-EPMC12733967 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature