Sperm DNA Fragmentation in Normozoospermic Men Is Associated with Blastocyst Formation and Quality in Conventional In Vitro Fertilization.

ABSTRACT: Background: Assisted reproductive therapy (ART) has been utilized as an effective therapeutic strategy for addressing infertility worldwide, and one of the key determinants of ART success is the acquisition of high-quality embryos through in vitro fertilization (IVF). We investigated which male factors were associated with embryo formation and quality in conventional IVF (cIVF). Methods: This study was an exploratory subanalysis of a trial conducted to examine the associations of clinical and lifestyle factors with sperm abnormalities in 41 men from infertile couples without identifiable male factors. From the original cohort, 21 men whose partners underwent cIVF were included for blastocyte outcome assessment. Semen samples were evaluated for standard sperm parameters and DN

SUBMITTER: Mori Y 

PROVIDER: S-EPMC12734054 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature