<i>Bifidobacterium adolescentis</i> Strengthens Gut Barrier in Post-Voyage Functional Constipation.

ABSTRACT: Prolonged periods of sailing may contribute to the development of functional constipation, which can significantly impair an individual's work efficiency. Currently, the efficacy of Bifidobacteria in treating functional constipation is gaining recognition. However, since the therapeutic effects of Bifidobacteria are strain-specific, further research is required on strains isolated from pre-voyage fecal samples. This study examines the role of gut microbiota in post-stroke constipation, aiming to identify specific microbial biomarkers for the development of targeted therapeutic strategies. B. adolescentis was identified through metagenomic analysis and subsequently isolated for validation. In the experimental group (EG), C57BL/6J mice received fecal suspension treatment

SUBMITTER: Zhao H 

PROVIDER: S-EPMC12734236 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature