Outpatient Management of Pulmonary Embolism Patients with Direct Oral Anticoagulants: A Systematic Review.

ABSTRACT: Background: Pulmonary embolism (PE) patients are generally admitted to the hospital, which leads to significant burden on healthcare systems. Many PE patients are hemodynamically stable and can be ambulated safely. Direct oral anticoagulants (DOACs) do not need routine laboratory monitoring, which makes them a convenient option for outpatient care. Data on the outpatient management of PE patients using DOACs are scarce. Methods: We conducted a systematic search of MECENTRAL databases to identify randomized controlled trials (RCTs), non-randomized studies (non-RCTs), retrospective studies, reviews, systematic reviews, meta-analyses, and clinical guidelines evaluating the use of DOACs for outpatient treatment of PE patients. Results: A total of 833 publications were iden

SUBMITTER: Khachatryan AS 

PROVIDER: S-EPMC12734285 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature