In Vivo Assessment of Anti-Inflammatory Effects of Aqueous Extracts of <i>Nepeta nuda</i> ssp. <i>nuda</i> L. in Experimental Model of Peripheral Inflammation in Male Long Evans Rats.

ABSTRACT: Background: Recently various plants have attracted considerable scientific interest as potential therapeutic alternatives to known drugs used in anti-inflammatory therapy. Therefore, we have investigated the possible anti-inflammatory and analgesic effects of aqueous extracts from flowers of the medical plant Nepeta nuda ssp. nuda L. (naked catmint) in a model of acute peripheral inflammation induced by intraplantar injection of λ-carrageenan in the hind paw of Long Evans rats. Methods: Two routes of N. nuda extract application were used: locally by intraplantar injections at dosages of 2.5 mg/kg and 25 mg/kg and systemically by intraperitoneal administration at dosages of 50 mg/kg and 200 mg/kg, respectively. Paw volume was measured prior to the carragee

SUBMITTER: Keremidarska-Markova M 

PROVIDER: S-EPMC12734412 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature