Effect of High-Pressure Processed Apples on Phenolic Metabolites, Short-Chain Fatty Acids, and Human Gut Microbiota Using a Dynamic In Vitro Colonic Fermentation System.

ABSTRACT: Background/Objectives: Consuming apples regularly has positive effects on human health due to their anti-inflammatory and antioxidant properties, which have been associated with their phenolic composition. To enhance the bioactive properties of apple phenolic compounds, high-pressure processing (HPP) has been studied as a tool to improve their extraction during gastrointestinal digestion with the aim of increasing their bioaccessibility and the amount that reaches the colon unchanged, which can serve as substrates for bacterial fermentation. This study aimed to analyze the impact of an HPP-apple ingredient on the metabolism of human gut microbiota using an in vitro dynamic simulator of gastrointestinal digestion and colonic fermentation (GID-CF) that allowed us to study the t

SUBMITTER: de Ancos B 

PROVIDER: S-EPMC12734438 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature