Is Mechanical Power the Trojan Horse? Emphasizing the Role of Driving Pressure.

ABSTRACT: Background and Objectives: Driving pressure (DP) and components of mechanical power (MP) have been proposed as prognostic markers in ARDS. The prognostic significance of these parameters in COVID-19-associated ARDS (C-ARDS), particularly during the early phase of intensive care unit (ICU) stay, remains uncertain. Materials and Methods: A retrospective single-center cohort of 310 C-ARDS patients receiving invasive mechanical ventilation was analyzed. Ventilator data from the first 72 h after ICU admission were retrieved. DP, total mechanical power (MPtot), and dynamic mechanical power (MPdyn) were calculated. The primary endpoint was defined as ICU mortality; secondary endpoints were ventilator-free days (VFDs) and length of stay (LOS) in ICU. ROC analyses, Cox proportional ha

SUBMITTER: Birtane D 

PROVIDER: S-EPMC12734470 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature