Associations Between Cognitive Performance and Motor Signs in Older Adults with Alzheimer's Dementia.

ABSTRACT: Background and Objectives: The interplay between motor tasks and cognition in Alzheimer's dementia (AD) remains insufficiently characterised. We hypothesised that prefrontal-mediated cognitive functions could contribute to motor impairments in older adults with AD. Materials and Methods: Cross-sectional data from the National Alzheimer's Coordinating Centre (NACC) were analysed. Our sample included older adults (≥60 years) with a baseline diagnosis of AD. The Unified Parkinson's Disease Rating Scale Part-III was used to assess the presence or absence of motor signs. Episodic memory, language, confrontation naming, attention, processing speed, and executive function were assessed using a neuropsychological battery. Binary logistic models examined the relationship between cogni

SUBMITTER: Liampas I 

PROVIDER: S-EPMC12734484 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature