Understanding Anxiety Symptoms of Mood Disorders Across Bipolar and Major Depressive Disorder Using Network Analysis.

ABSTRACT: Background and Objectives: Anxiety is prevalent in patients with major depressive disorder (MDD) and bipolar disorder (BD). Understanding its interaction with mood disorders may provide deeper insight into symptom clustering, severity, and interventions. We compared the networks of MDD and BD using the Beck Anxiety Inventory (BAI) to identify central symptoms and interconnections. Materials and Methods: This cross-sectional study involved 815 individuals with MDD (n = 332) and BD (n = 483) who had clinically significant anxiety symptoms (BAI score > 8). Network analysis identified anxiety symptom clusters. Network centrality, stability, and comparison tests assessed the structural differences and global strength variations between the groups. Results: Bot

SUBMITTER: Kwon SS 

PROVIDER: S-EPMC12734980 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature