Microbial Imbalance and Stochastic Assembly Drive Gut Dysbiosis in White-Gill Diseased <i>Larimichthys crocea</i> (Richardson, 1846).

ABSTRACT: White-gill disease has emerged as one of the major health threats in large yellow croaker Larimichthys crocea (Richardson, 1846) aquaculture, yet its underlying microbial mechanisms remain poorly understood. In this study, we investigated the gut microbiota of healthy and white-gill diseased L. crocea across different growth stages and aquaculture locations using 16S rRNA gene amplicon sequencing and bioinformatics analysis. Across both juvenile and adult fish, as well as multiple sampling locations, diseased individuals consistently exhibited significantly reduced microbial richness and evenness compared to healthy counterparts, along with a clear divergence in community composition. Notably, the relative abundance of Photobacterium damselae subsp. damselae was

SUBMITTER: Wang X 

PROVIDER: S-EPMC12735229 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature