The Characteristics of Patients That Develop Severe Leptospirosis: A Scoping Review.

ABSTRACT: This scoping review of original literature published before 1 March 2025 examined the demographic and simple clinical and laboratory findings associated with the development of severe leptospirosis. The definition of severe leptospirosis varied in different studies, but for the purposes of this review it included death or patients with a more complicated clinical course. There were 35 articles that satisfied the review's inclusion criteria. Increasing age was associated with severe disease in 7 studies. Abnormal respiratory examination findings (18 studies), hypotension (11 studies), oliguria (8 studies), jaundice (7 studies) and altered mental status (4 studies) also helped identify high-risk patients. Abnormal laboratory tests-specifically the complete blood count (17 studies), measures

SUBMITTER: Rosengren P 

PROVIDER: S-EPMC12735429 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature