Inhibition of <i>Escherichia coli</i> O157:H7 Growth Through Nutrient Competition by Non-O157 <i>E. coli</i> Isolated from Cattle.

ABSTRACT: Escherichia coli O157:H7 is a major food safety concern through contamination of beef and produce. Non-antibiotic interventions to minimize O157:H7 in food animals and products are highly desired and one strategy to improve food safety is to reduce O157:H7 in cattle, a main asymptomatic reservoir, through probiotic administration. Non-pathogenic E. coli populating the intestine represent a compelling probiotic source, as these strains are already host-adapted. The challenge is to identify non-pathogenic strains capable of competing with O157:H7 for nutrients or those producing compounds to inhibit O157:H7 growth. Here, E. coli isolated from cattle fecal and recto-anal junction swab samples were sequenced and screened for the ability to compete with O157:H7. Fourteen ge

SUBMITTER: Maki JJ 

PROVIDER: S-EPMC12735539 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature