Evaluation of Risk Determinants and Molecular Characterisation for Non-Primate Hepacivirus Infection in Turkish Horses.

ABSTRACT: The genus Hepacivirus (HCV) has long been a dynamic group, increasing its number by myriads of species collectively referred to as non-primate hepaciviruses (NPHVs). NPHV exhibits a broad hepatotropism and is often attributed to chronic infection in horses and dogs. However, recent studies and meta-analyses on NPHV in horses have remained inconclusive regarding the determination of risk factors for infection. Therefore, our main goal was to investigate the frequencies and molecular characteristics of NPHV infection linked to geographical location, horse breeds, genders, and ages. For this purpose, we tested the positivity of 152 samples collected from ten cities in Turkey by conventional PCR, targeting the highly conserved 5' UTR sequence, and compiled our results with pedigree data

SUBMITTER: Atasoy MO 

PROVIDER: S-EPMC12735631 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature