Comparative Effectiveness of Different Probiotic Delivery Methods in Oral Candidiasis: A Systematic Review.

ABSTRACT: Oral candidiasis, mainly from Candida albicans, affects immunocompromised individuals, the elderly, and denture wearers. Probiotics offer immunomodulatory and microbiota-balancing benefits as potential antifungal alternatives. However, the comparative impact of different probiotic delivery methods remains inadequately explored. This systematic review evaluated the effectiveness of various probiotic delivery methods in reducing Candida colonization and clinical symptoms in oral candidiasis. Following PRISMA 2020 guidelines, a systematic review search across multiple databases included human clinical studies based (Medline, Web of Science, ScienceDirect, and ProQuest) on PICO criteria across all age groups. Outcomes assessed included Candida load, oral microbiota changes

SUBMITTER: Ashouritoustani R 

PROVIDER: S-EPMC12735766 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature