Importance of Different Parameters for Monitoring Dogs with <i>Leishmania infantum</i> Infections in a Non-Endemic Country.

ABSTRACT: Leishmania (L.) infantum infections in dogs can cause severe recurrent disease. The aim of this study was to investigate different parameters for early detection of disease relapses in L. infantum-infected dogs in Germany. Fifty-two dogs naturally infected with L. infantum were enrolled. During the one-year study period, all dogs remained outside of endemic areas and attended study appointments every three months, including physical examination, blood pressure measurement, complete blood count with differential, serum biochemistry with symmetrical dimethylarginine and C-reactive protein, complete urinalysis including urine protein-to-creatinine ratio, L. infantum PCR, and antibody ELISA. Disease relapse was defined as deterioration of clinical or laboratory para

SUBMITTER: Kaempfle M 

PROVIDER: S-EPMC12735808 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature