TD-NMR-Based Determination of the Entrapped Water Yield of Water-in-Oil-in-Water Double Emulsions: Influence of Xanthan Gum Addition.

ABSTRACT: Water-in-oil-in-water (W/O/W) double emulsions (DEs) are considered promising systems for encapsulating, protecting, and delivering hydrophilic compounds. However, their thermodynamic instability limits their practical application. The addition of stabilizers and/or thickeners is a straightforward strategy to improve their stability. However, the high viscosity of DEs complicates the accurate determination of their entrapped water yield (EY), especially when applying techniques based on phase separation. In this study, two TD-NMR-based techniques (T₂ relaxometry, and NMR diffusometry) were compared to analytical photocentrifugation to evaluate their effectiveness in determining the entrapped water yield of DEs formulated with various concentrations (0-0.8 wt%) of xanthan

SUBMITTER: Hu Y 

PROVIDER: S-EPMC12735952 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature