The Effect of the Extraction Method on the Content of Bioactive Compounds and the Biological Activity of <i>Nigella sativa</i> Extracts.

ABSTRACT: Ensuring food safety and consumer health are crucial elements of sustainable food safety management, requiring the use of substances that inhibit the growth of undesirable microorganisms at various stages of production. The negative impact of many of these on human health and the environment has led to increased interest in alternative solutions, such as plant extracts. The aim of this study was to determine the biological activity of extracts obtained from Nigella sativa seeds using various methods, including Soxhlet and ultrasound-assisted extraction (UAE) using hexane and methanol and supercritical CO₂ extraction (SFE) assisted with methanol. The content of polyphenolic compounds, their composition, and biological activity depended on the extraction method and solvent

SUBMITTER: Gwiazdowski R 

PROVIDER: S-EPMC12736113 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature