Isolation of <i>Monascus purpureus</i> HC-5 and Optimization of Solid-State Fermentation for High-Yield Pigment Production.

ABSTRACT: Monascus pigments (MPs) are valuable natural colorants, but their industrial production is often hampered by scarce high-yield strains and inefficient processes. In this study, a novel MPs-producing strain was isolated from red yeast rice and named as Monascus purpureus HC-5. This strain exhibited notable hydrolase activities, indicating a high efficiency in substrate utilization. In addition, using rice as the optimal substrate, the key parameters of solid-state fermentation were optimized. Response surface analysis revealed that soaking time and temperature were the most critical influencing factors. The optimal combination conditions were an inoculum size of 8.91%, a soaking time of 13.59 h, and a temperature of 32 °C. Under these optimized conditions, the MPs yield reache

SUBMITTER: Quan W 

PROVIDER: S-EPMC12736185 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature