Natural Phytotherapeutics in Dermatology and Cosmetology: Bioactive Potential of Grape Pomace on Human Skin Fibroblasts.

ABSTRACT: The aim of the study was to assess the biological potential of extracts obtained from the grape pomace of three Vitis vinifera hybrid varieties-Regent, Rondo and Marechal Foch-as a natural source of bioactive compounds, with possible application in cosmetology and dermatology. Grape pomace, which is an important by-product of the winemaking process, is a rich source of polyphenols, flavonoids, anthocyanins and vitamin C, which exhibit antioxidant, anti-inflammatory and cytoprotective properties that are important for skin health. The conducted studies determined the antioxidant activity of the extracts (DPPH) and the content of total phenolic compounds, flavonoids, anthocyanins and vitamin C, Of the varieties analysed: Marechal Foch exhibited the highest antioxidant activity (10 µmo

SUBMITTER: Domagala B 

PROVIDER: S-EPMC12736252 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature