The Potential Mediating Role of Inflammation on the Association Between Dietary Inflammatory Index and Sleep Disturbance Among Breast Cancer Patients: A Cross-Sectional Study.

ABSTRACT: Background: Sleep disturbance (SD) is very common in breast cancer (BC) patients, resulting in poor therapeutic efficacy and prognosis. Diet may be associated with SD through systemic inflammation. This study aimed to evaluate the association between the energy-adjusted Dietary Inflammatory Index (E-DII) and SD, as well as the potential mediating role of inflammatory biomarkers in patients with BC. Methods: In this cross-sectional study, 302 BC patients were recruited, from whom 103 blood samples were obtained for the determination of plasma inflammatory biomarkers. Dietary intake was evaluated using 3-day, 24 h dietary recalls, while SD was assessed using the Pittsburgh Sleep Quality Index (PSQI). Results: SD was observed in 91 (30.13%) patients, who exhibited signifi

SUBMITTER: Huang Z 

PROVIDER: S-EPMC12736269 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature