Surface Modifications of Zinc Oxide Particles with Chitosan, Polyethylene Glycol, Polyvinyl Alcohol, and Polyvinylpyrrolidone as Antibacterial Agents.

ABSTRACT: To investigate the effect of nanoparticle reinforcement, polymer blends (M8) comprising polyvinyl alcohol, polyvinylpyrrolidone, polyethylene glycol, and chitosan were modified using zinc oxide particles (M8/ZnO). This study introduces an M8-modified ZnO composite that offers a non-antibiotic approach relevant to antimicrobial resistance. The average particle size of the ZnO particles was determined to be 181.8 nm using scanning electron microscope (SEM) analysis. Based on the inhibition percentage, M8 has a minimum inhibition concentration (MIC) to have at least a 50% inhibition, or MIC50 value, against Pseudomonas aeruginosa (PA) and Salmonella enterica (SE) at 12.5 and 25% of M8, respectively. The MIC with at least a 90% inhibition percentage, or MIC90, of M8 against SE an

SUBMITTER: Doan L 

PROVIDER: S-EPMC12737094 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature