Systematic Review and Meta-Analysis of Treatments on Melasma Area Severity Index and Quality of Life.

ABSTRACT: Background: Melasma is a chronic skin condition resulting from increased melanogenic activity, which induces a significant emotional impact on the patient's quality of life. The efficacy of melasma treatments depends on individual response and on the chosen therapeutic approach, which may include topical skin-lightening agents, oral drugs, and chemical peels. Objectives: We aimed to evaluate the reported efficacy of treatment techniques on melasma control and patients' quality of life through a systematic review and meta-analysis, as well as to investigate a putative relationship between melasma severity and quality of life. Methods: Following PRISMA guidelines, we collected data from PubMed, Scopus, and Embase databases. The eligibility criteria included studies that

SUBMITTER: Ribeiro MM 

PROVIDER: S-EPMC12737163 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature