Spatial Analysis of Drug-Resistant Tuberculosis in Colombia (2020-2023): Departmental Rates, Clusters, and Associated Factors.

ABSTRACT:

Background

Drug-resistant tuberculosis (DR-TB) constitutes a serious threat to global public health due to the increase in strains resistant to multiple drugs, especially isoniazid and rifampicin. This resistance increases mortality, estimated at 25.6% globally, and complicates treatments due to its high toxicity and cost.

Materials and methods

A quantitative ecological study was carried out with data on drug-resistant tuberculosis reported in Sivigila in the years (2020-2023) SIVIGILA database. 1694 cases were analyzed, considering sociodemographic variables such as age, sex, nationality and prioritized population groups. Departmental rates per 100,000 inhabitants were calculated with DANE projection, from these choropleth maps were developed. Applying a Kulldorff spatial s

SUBMITTER: Patino-Palma B 

PROVIDER: S-EPMC12737329 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature