Molecular Epidemiological Investigation and Viral Isolation of Porcine Rotavirus in Southwest China During 2024-2025.

ABSTRACT: In 2023, the detection rate of porcine rotavirus (PoRV) surpassed that of porcine epidemic diarrhea virus (PEDV) for the first time, establishing PoRV as the predominant pathogen responsible for viral diarrhea in pigs. To systematically investigate the epidemiology and molecular characteristics of PoRV in Southwest China, a total of 196 diarrheal clinical samples were collected from 29 large-scale pig farms across the region during 2024-2025. RT-qPCR results revealed a high PoRV positivity rate of 57.14% (112/196) with group A porcine rotavirus (PoRVA) being the most prevalent at 46.43%, representing the predominant group. Genotyping and phylogenetic analysis of the VP4 and VP7 genes indicated that the P genotype P[13] was most prevalent (77.78%, 21/27), while the major G genotypes were G4

SUBMITTER: He S 

PROVIDER: S-EPMC12737377 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature