Cytotoxic Activity of the Baltic Cyanobacterium <i>Pseudanabaena galeata</i> CCNP1313.

ABSTRACT: While tropical regions have traditionally been the focus of studies on natural bioactive products, works published within the last decade demonstrate that cyanobacteria from the Baltic Sea also possess significant biotechnological and pharmaceutical potential. The Baltic Pseudanabaena galeata CCNP1313 previously demonstrated activity against breast cancer cell lines (MCF7 and T47D) and several viruses. In the present study, the cytotoxicity of cellular extract and flash chromatography fractions from the strain were evaluated against a wider panel of cancer cells (A549, C-33A, CaSki, DoTC2, HeLa, PC3, SiHa, and T47D). To gain better insight into the compounds potentially responsible for the observed effects, high-resolution mass spectrometry was combined with bioactivity-based molecu

SUBMITTER: Ceglowska M 

PROVIDER: S-EPMC12737398 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature