Characterization of Novel <i>Przondovirus</i> Phage Adeo Infecting <i>Klebsiella pneumoniae</i> of the K39 Capsular Type.

ABSTRACT: Klebsiella pneumoniae is one of the most significant nosocomial pathogens and an important cause of human infections worldwide. The microorganism is capable of producing different capsular polysaccharides (CPSs), which are the primary receptors for capsule-specific K. pneumoniae bacteriophages encoding tailspike proteins (TSPs) with polysaccharide-degrading activity. In this study, the novel virulent Przondovirus phage Adeo was isolated and characterized. The phage was able to infect K. pneumoniae strain with a K39 capsular polysaccharide structure. The morphology, biological properties, stability, and genomic organization of Adeo were studied. Comparative genomic and phylogenetic analyses were performed to establish the relationship between the phage and other

SUBMITTER: Kolupaeva NV 

PROVIDER: S-EPMC12737672 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature