Detection of Lymphocytic Choriomeningitis Virus in House Mouse (<i>Mus musculus</i>) in Brazil.

ABSTRACT: The lymphocytic choriomeningitis virus (LCMV) is an under-investigated rodent-borne arenavirus primarily associated with its natural reservoir, the cosmopolitan rodent Mus musculus. Although widely distributed in mice worldwide, human cases are rare, likely under-reported, and often misdiagnosed. While typically asymptomatic or self-limiting, infection can progress to neurological disease, severe congenital outcomes, or fatal illness in transplant recipients. Despite its public health relevance, this study provides the first detection and characterization of LCMV in Brazil. We analyzed 236 rodent serum samples and 78 tissue samples from synanthropic rodents (Mus musculus, Rattus rattus, and Rattus norvegicus) collected during seven independent expeditions across

SUBMITTER: Cavalcanti GR 

PROVIDER: S-EPMC12737706 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature