Short-term associations between ambient air pollution and emergency department visits for Parkinson disease, multiple sclerosis, migraine, and seizure in California, 2005-2018.

ABSTRACT:

Background

Previous studies have linked ambient air pollution to worsening neurological conditions, but research in the United States is limited. This study aims to investigate short-term associations between emergency department (ED) visits for four disorders affecting the nervous system (Parkinson disease, multiple sclerosis, migraine, and seizure) and three major air pollutants: fine particulate matter (PM_2.5), carbon monoxide (CO), and nitrogen dioxide (NO₂).

Methods

Daily estimated exposure concentrations at 12 km were aggregated to the ZIP-code level and linked to 6 million ED visits in California (2005-2018). Using a time-stratified case-crossover design with conditional quasi-Poisson regression, we evaluated lag-specific associations and stratif

SUBMITTER: Chen S 

PROVIDER: S-EPMC12737864 | biostudies-literature | 2026 Feb

REPOSITORIES: biostudies-literature