Breast Implant Illness: Symptoms, Outcomes with Explantation and Potential Etiologies-A Systematic Review and Meta-analysis.

ABSTRACT:

Background

Breast Implant Illness (BII) is a controversial condition characterized by a broad spectrum of systemic symptoms reported by patients with breast implants, leading to an increase in explantation procedures. Its mechanisms remain unclear, with hypotheses including immune responses, microbial colonization, and psychological factors. This study analyzes potential causes, common symptoms, and the impact of explantation on symptom resolution.

Methods

A systematic review following PRISMA guidelines was conducted using PubMed, Web of Science, and Scopus databases. Studies on BII symptoms and outcomes were screened based on predefined criteria. Data on demographics, implant characteristics, symptoms, explantation outcomes and potencial etiologies were extracted. Meta-anal

SUBMITTER: Ferreira S 

PROVIDER: S-EPMC12738613 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature