Assessing the generation and dispersal of respiratory particles using upper respiratory commensal bacteria as index organisms for respiratory pathogens.

ABSTRACT: There is a need to better understand the dispersal and spread of respiratory pathogens. However, carrying out controlled microbiology-based simulation studies is difficult, particularly if the target organism is highly pathogenic or is currently unknown. An alternative approach is to use commensal upper respiratory tract (URT) bacteria as index organisms. Healthy volunteers were asked to perform defined respiratory activities within a purpose-built flexible-film isolator. The dispersal of large (L-RPs) and small respiratory particles (S-RPs) was assessed via passive (settle plates) and active air sampling, respectively. Activities were carried out with or without a face covering. Dispersal of respiratory particles differed with individual. During speech, increased vocal volume was associat

SUBMITTER: Barkoci P 

PROVIDER: S-EPMC12738709 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature