Development of a 3D-printable bioactive polycaprolactone-collagen peptides filament for biomedical applications.

ABSTRACT: This study presents a scalable, nontoxic method for fabricating a 3D printable polycaprolactone (PCL)-collagen peptides composite filament via solvent-assisted blending and a customized desktop filament extrusion system. Virgin and recycled PCL feedstocks were used to study the matrix characteristics. Scanning electron microscopy, X-ray diffraction, differential scanning calorimetry, thermogravimetric analysis, and intrinsic fluorescence spectroscopy confirmed that the composite maintains PCL's inherent crystalline and thermal properties. It also exhibits intrinsic bioactive capabilities provided by the collagen peptides. Filaments with diameters suitable for the Fused Filament Fabrication 3D printing were obtained. Tests demonstrated that the recycled matrix and the lab-scale process redu

SUBMITTER: Cantella S 

PROVIDER: S-EPMC12738878 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature