Development, validation, and web deployment of a rebleeding risk prediction model for acute non-variceal upper gastrointestinal bleeding in a Chinese population.

ABSTRACT:

Background

Acute non-variceal upper gastrointestinal bleeding (ANVUGIB) is a common life-threatening emergency. Despite advances in endoscopic hemostasis, the 7-day rebleeding rate remains as high as 15-30%. Existing risk assessment tools show limited performance in Chinese populations, underscoring the need for a high-precision model tailored to local patients.

Objective

To develop, validate, and deploy an individualized model for predicting 7-day rebleeding risk in Chinese patients with ANVUGIB using early clinical information.

Methods

We retrospectively included 818 patients with ANVUGIB treated at the General Hospital of Central Theater Command between January 2020 and December 2023, randomly divided into a training cohort (n = 572) and an internal validati

SUBMITTER: Chen Y 

PROVIDER: S-EPMC12738914 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature