Probiotic modulation of maternal gut and milk microbiota and potential implications for infant microbial development in the perinatal period.

ABSTRACT:

Background

Probiotics are live microorganisms that may enhance or restore gut microbiota. They are often recommended during pregnancy and infancy for potential benefits, but evidence is inconclusive. This study aimed to investigate probiotic supplementation's effects on maternal and infant gut and milk microbiota and its link to nutrient intake during pregnancy.

Method

A total of 23 pregnant women were enrolled and divided into a probiotic group (n = 11) and a non-probiotic control group (n=12). Probiotic effects were evaluated through fecal and milk microbiota analysis via 16S rRNA gene sequencing. Nutrient intake data were collected to assess differences linked to probiotics. Key microbiota diversity and richness were analyzed using linear discriminant analysis effect size

SUBMITTER: Tye KD 

PROVIDER: S-EPMC12738936 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature