Urine-based HIV-1 self-testing in China: A cross-sectional diagnostic accuracy and usability study.

ABSTRACT: Expanding HIV testing coverage is essential to achieving the first target of the UNAIDS 95-95-95 goals. Under current circumstances, a novel testing method, urine-based HIV self-testing (HIVST) will be essential to reach undiagnosed people living with HIV. This multicenter cross-sectional study conducted in three sites in China evaluated the diagnostic accuracy, usability, and acceptability of urine-based HIVST in untrained users under real-world conditions. Among 1,495 participants, the urine test demonstrated a sensitivity of 99.44% and a specificity of 100.00%, with perfect agreement between self-testers and professionals. Agreement between home-based and facility-based testing was 100.00%, confirming the reliability of self-testing in unsupervised settings. Most participants were able

SUBMITTER: Niu M 

PROVIDER: S-EPMC12739172 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature