Age and liver transplantation: a key factor in clinical outcomes? single center study in Argentina.

ABSTRACT:

Introduction

Growing demand for liver transplantation (LTx) has increased the use of elderly donors. In Argentina, however, data on the clinical impact of donor age on post-transplant outcomes remain limited.

Objective

To evaluate the effect of donor age on clinical, functional, and molecular outcomes after LTx at Hospital Universitario Fundación Favaloro Buenos Aires, Argentina.

Methods

We performed a retrospective cohort study of 494 LTx conducted between 2009 and 2020. Patients were stratified into two age groups: 18-59 years (Younger) and ≥60 years (Elderly). Overall and graft survival (OS and GS) were assessed using Kaplan-Meier and Cox regression analyses adjusted for recipient age, donor age, recipient gender, donor gender, transplant year, MELD score, disease

SUBMITTER: Santillan Pazmino M 

PROVIDER: S-EPMC12739379 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature